There are 3 different ways, I think:
1) Break Tackle, Block - to make him perfect cage breaker and blitzer
2) Block, Mighty Blow - to make him killer like Big Guy (to have 2 of them

3) Block, Guard - to make him a big unpassable wall
I like the first one most, but maybe U have different opinions - any advise is welcome.
I don't think U need to know about other players in team. Maybe just that I have AG4+sidestep skink, too. Those are the players I want to make a team around.